![]() Most seem to be caused by a complex mix of risk factors, some environmental and some genetic or hereditary.įor most cases of soft tissue sarcomas, no direct cause has been determined for their development. Very few tumors and cancers have a single known cause. The reason why a particular pet may develop this, or any tumor or cancer, is not straightforward. "Soft tissue sarcomas make up about 15% of cancers of the skin affecting dogs and about 7% of those affecting cats."Įven though soft tissue tumors arise from many different types of cells, they all behave in a similar manner and their treatment is typically the same. Fibrosarcomas are common in dogs and are a type of soft tissue sarcoma (see handout "Fibrosarcoma in Dogs" for more information). Soft tissue sarcomas make up about 15% of cancers of the skin affecting dogs and about 7% of those affecting cats. Connective, muscle, and nervous tissues are present throughout the entire body therefore, these tumors can develop over the chest, back, side, legs, and facial tissues of your pet. These tumors are the result of abnormal production of these cell types in an uncontrolled manner. ![]() © 2015 American College of Veterinary Radiology.Soft tissue sarcomas are a broad category of tumors including those that arise from the connective, muscle, or nervous tissues in dogs and cats. The high frequency of abdominal effusion with GIST's was of unknown etiology could possibly have been due to septic peritonitis.Ĭanine cecum gastrointestinal stromal tumor ultrasound. Similar to previous studies, GISTs appeared to be the most common spindle cell tumor associated with the cecum in our sample of dogs. Besides location, there were no unique ultrasound features of GISTs that would allow distinction from other gastrointestinal spindle cell tumors. There was overlap between the anatomical locations of all tumors types with the exception of the cecum where all eight tumors identified were GISTs. Gastrointestinal stromal tumors were significantly more likely to be associated (P < 0.03) with abdominal effusion than other tumor types. Tumor types included 19 GISTs, eight leiomyosarcomas, six leiomyomas, and four nonspecified sarcomas. Ultrasonographic features recorded examined included mass echogenicity, homogeneity, presence of cavitation, layer of origin, bowel wall symmetry, and loss of wall layering, location, size, vascularity, and evidence of perforation or ulceration. Immunohistochemistry staining was performed for retrieved tissue samples to further differentiate the tumor type and each sample was interpreted by a single veterinary pathologist. Thirty-seven dogs with an ultrasonographically visible gastrointestinal mass and a histopathologic diagnosis of spindle cell neoplasia were examined. The objective of this retrospective, cross-sectional study was to describe ultrasonographic features of canine GISTs compared with other spindle cell tumors. To our knowledge, no imaging features have been described in immunostochemically confirmed canine GISTs. Canine gastrointestinal stromal tumors (GISTs) are a recent subtype of gastrointestinal spindle cell tumor recognized with the increasing use of immunohistochemistry.
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